Transposable Elements and Stress in Vertebrates: An Overview

Since their identification as genomic regulatory elements, Transposable Elements (TEs) were considered, at first, molecular parasites and later as an important source of genetic diversity and regulatory innovations. In vertebrates in particular, TEs have been recognized as playing an important role in major evolutionary transitions and biodiversity. Moreover, in the last decade, a significant number of papers has been published highlighting a correlation between TE activity and exposition to environmental stresses and dietary factors. In this review we present an overview of the impact of TEs in vertebrate genomes, report the silencing mechanisms adopted by host genomes to regulate TE activity, and finally we explore the effects of environmental and dietary factor exposures on TE activity in mammals, which is the most studied group among vertebrates. The studies here reported evidence that several factors can induce changes in the epigenetic status of TEs and silencing mechanisms leading to their activation with consequent effects on the host genome. The study of TE can represent a future challenge for research for developing effective markers able to detect precocious epigenetic changes and prevent human diseases.     

涪陵地区茅三段热液白云岩展布影响因素分析

针对热液白云岩展布非均质性强的问题,开展基底断裂与茅三段沉积演化关系研究,分析断裂样式与白云岩分布关系,建立沉积演化模式,预测白云岩的分布。研究结果表明:茅三段可划分为5个小层,1~3小层为白云岩发育主要时期,4~5小层为台地均一化时期,不发育白云岩;15-1、15-2和16号基底断裂控制了早期“台-洼”相间的沉积地貌,断裂附近的地貌高部位为生屑滩发育有利部位,为白云岩的发育提供物质基础;15-1、15-2号基底断裂样式为花状,周边生屑滩白云石化程度高,为白云岩发育最有利区;16号基底断裂为直立状,附近白云石化发育程度较低,为白云岩发育较有利区。研究成果可为热液白云岩领域的进一步勘探提供指导依据。     

高职院校学生创业意向影响因素研究

采取简单随机方法,从菏泽家政职业学院各个系随机选取6个班,以笔者自拟的调查问卷对该6个班的全体学生进行问卷调查,并采用二元logistic回归分析对问卷调查的结果进行多因素分析,最后得出结论,性别、所学专业、专业知识和技能、家人态度、创业资金来源、他人影响对高职院校学生创业意向的影响不显著,而内控制源、创业能效感、风险忍耐度、政府支持对高职院校学生创业意向有显著影响。     

Muddling between science and engineering: an epistemic strategy for developing human factors and ergonomics as a hybrid discipline

Human Factors and Ergonomics (HFE) recognises itself as a design-driven, systemic and scientific discipline geared towards well-being and performance. Being a scientific discipline and design-oriented requires that the epistemic basis of science and design/engineering be fully comprehended. In interdisciplinary research where these two viewpoints meet, there are often dilemmas posed in terms of knowledge construction and labelling of activity. Therefore, this article scrutinises these two orientations and addresses the differences and commonalities, using case studies from engineering and psychological science (both constituents of HFE). Based on these insights, a way forward is suggested in terms of (1) a reflexive engagement with epistemic concepts and methods; (2) finding a conceptual space for balancing and bridging the science-engineering divide; (3) comprehending ‘design-thinking/design knowledge’ and not treating it as an application of science; (4) providing emphasis on problem formulation and practices of HFE focusing on developing them in systemic terms.     

中国省际绿色技术创新效率测度及影响因素研究

文章基于2011—2017年中国30个省份面板数据，运用super-SBM模型对绿色技术创新效率进行测算，并利用ML指数对绿色技术创新效率进行动态分析，最后通过空间滞后模型分析影响效率的关键因素。研究结果表明：中国绿色技术创新效率呈逐渐增长的趋势，但整体效率偏低，有较大进步空间；中国绿色技术创新效率存在明显区域差异，呈现由东部向西部递减的格局；绿色技术创新水平的提高是技术效率和技术进步共同贡献的结果；产业结构、区域开放程度和教育水平对绿色技术创新效率产生积极的正向影响，环境规制和研发投入强度对绿色技术创新效率影响不显著。     

腾冲市茨竹地铁多金属矿成矿地质特征及控矿因素

腾冲市茨竹地铁多金属矿现目前是一座正在开采的以磁铁矿为主、共（伴）生锡钨矿的小型矿山。为了增加矿山资源储量、延长矿山服务年限，通过对矿区的地质特征阐述和对矿区地层岩性、构造、岩体等控矿因素的分析研究，总结了矿区成矿规律并形成了矿区的成矿模式，为矿区深部探矿、外围找矿提供了一定的理论依据。